What is an expected outcome of successful LAAO in patients with atrial fibrillation?

The expected outcome of successful Left Atrial Appendage Occlusion (LAAO) in patients with atrial fibrillation is a reduction in the risk of stroke over time. The procedure specifically targets the left atrial appendage, where blood clots often form in patients with atrial fibrillation. By occluding this appendage, LAAO decreases the likelihood of thrombus formation and subsequent embolic events, such as strokes.

While many patients may see improvements in their overall heart rhythm and some might experience fewer symptoms related to atrial fibrillation, LAAO does not guarantee the complete elimination of the arrhythmia itself. Therefore, while symptoms may improve and some patients might maintain a stable heart rhythm, it is not a definitive cure for atrial fibrillation.

Furthermore, lifelong anticoagulant therapy may still be necessary for some patients post-procedure depending on individual risk factors and the absence of LAAO, meaning that stopping anticoagulation isn't a universal outcome. Lastly, while patients may experience improved physical activity levels post-procedure, this is not the primary goal of LAAO; the main focus is on stroke prevention. Thus, the emphasis on stroke risk reduction aligns with the primary clinical objective of LAAO.